Nebido 1000 mg 4 ml solution for injection Patient Information Leaflet PIL emc
Local guidelines for safety monitoring under testosterone replacement therapy should be taken into consideration. Measurements should be performed at the end of an injection interval and clinical symptoms considered. These serum levels should https://villaamericanaeventos.com.br/2024/10/02/anapolon-oxymetholone-50-mg-abdi-ibrahim-results/ be within the lower third of the normal range.
NEBIDO Solution for injection
- Testosterone is the most important androgen of the male, mainly synthesised in the testicles, and to a small extent in the adrenal cortex.
- With an injection, you can ensure that your testosterone takes a very fast effect and makes it easier for you to overcome the side effects of low testosterone.
- Each ml solution for injection contains 250 mg testosterone undecanoate corresponding to 157.9 mg testosterone.
Fertility studies in rodents and primates have shown that treatment with testosterone can impair fertility by suppressing spermatogenesis in a dosedependent manner. The undecanoic acid is metabolised by B-oxidation in the same way as other aliphatic carboxylic acids. The major active metabolites of testosterone are oestradiol and dihydrotestosterone.
SUMMARY OF PRODUCT CHARACTERISTICS
In case of treatment continuation, further measures should be taken to minimise the individual VTE risk. Testosterone replacement therapy for male hypogonadism when testosterone deficiency has been confirmed by clinical features and biochemical tests (see section 4.4). Each ampoule / vial with 4 ml solution for injection contains 1000 mg testosterone undecanoate corresponding to 631.5 mg testosterone. If you know your total testosterone reading from a previous blood test input the results to the left above to see if your testosterone levels are normal.
Abuse of testosterone, especially if you take too much of this medicine alone or with other anabolic androgenic steroids, can cause serious health problems to your heart and blood vessels (that can lead to death), mental health and/or the liver. Following intramuscular administration of this depot formulation the release rate is characterised by a half life of 90± 40 days. If severe upper abdominal complaints, liver enlargement or signs of intra-abdominal haemorrhage occur in men using Nebido, a liver tumour should be included in the differential-diagnostic considerations. The use of Nebido is contraindicated in men with past or present liver tumours (see section 4.3).
The lymphatic system is a network of vessels that drains fluid from tissues throughout the body, eventually delivering it back to the bloodstream. This unique delivery system allows for a sustained release of testosterone, minimizing the need for frequent injections. In patients suffering from severe cardiac, hepatic or renal insufficiency or ischaemic heart disease, treatment with testosterone may cause severe complications characterised by oedema with or without congestive cardiac failure.